human SRD5A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SRD5A2.
shAAV-224315
AAV-h-SRD5A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SRD5A2 (steroid 5 alpha-reductase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
SRD5A2 encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
Gene ID
6716
Gene Name (Vector)
steroid 5 alpha-reductase 2
Gene Symbol
SRD5A2
HGNC ID
HGNC:11285
ORF Size (aa)
765
RefSeq ID
NM_000348
RefSeq Synonyms
NM_000348, BC113641, BC112252,
Species
human
UniGene ID
Hs.458345
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.