human SPIRE1 shRNA silencing AAV

Name
AAV-h-SPIRE1-shRNA

Cat No
shAAV-224208

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SPIRE1.

shAAV-224208

AAV-h-SPIRE1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPIRE1 (spire type actin nucleation factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Spir-1

Description (Vector)

Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 (PubMed 11747823)).(supplied by OMIM, Mar 2008)

Gene ID

56907

Gene Name (Vector)

spire type actin nucleation factor 1

Gene Symbol

SPIRE1

HGNC ID

HGNC:30622

ORF Size (aa)

1794

ORF Size (bp)

1794 bp

RefSeq ID

NM_020148

RefSeq Synonyms

NM_020148, NM_001128627, NM_001128626, BC125207, BC125206, BC115005, BC016825,

Species

human

UniGene ID

Hs.515283

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.