human SPINK1 shRNA silencing AAV

Name
AAV-h-SPINK1-shRNA

Cat No
shAAV-224184

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SPINK1.

shAAV-224184

AAV-h-SPINK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPINK1 (serine peptidase inhibitor, Kazal type 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PCTT; PSTI; Spink3; TATI; TCP

Description (Vector)

SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.

Gene ID

6690

Gene Name (Vector)

serine peptidase inhibitor, Kazal type 1

Gene Symbol

SPINK1

HGNC ID

HGNC:11244

ORF Size (aa)

240

RefSeq ID

NM_003122

RefSeq Synonyms

NM_003122, BC025790,

Species

human

UniGene ID

Hs.407856

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.