human SPESP1 shRNA silencing AAV

Name 
AAV-h-SPESP1-shRNA
Cat No 
shAAV-224157
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NOX5.

shAAV-224157
AAV-h-SPESP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOX5 (NADPH oxidase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
NOX5 is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
79400
Gene Name (Vector)
NADPH oxidase 5
Gene Symbol
NOX5
HGNC ID
HGNC:14874
ORF Size (aa)
2160
ORF Size (bp)
2160 bp
RefSeq ID
NM_024505
RefSeq Synonyms
NM_024505, NM_001184780, NM_001184779, BC125098, BC125097,
Species
human
UniGene ID
Hs.657932

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.