human SP6 shRNA silencing AAV

Name
AAV-h-SP6-shRNA

Cat No
shAAV-224048

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SP6.

shAAV-224048

AAV-h-SP6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SP6 (Sp6 transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EPFN; EPIPROFIN; KLF14

Description (Vector)

SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 (PubMed 11087666)).(supplied by OMIM, Mar 2008)

Gene ID

80320

Gene Name (Vector)

Sp6 transcription factor

Gene Symbol

SP6

HGNC ID

HGNC:14530

ORF Size (aa)

1131

ORF Size (bp)

1131 bp

RefSeq ID

NM_199262

RefSeq Synonyms

NM_199262, NM_001258248, BC103954, BC103953, BC103952, BC103951,

Species

human

UniGene ID

Hs.253603

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.