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human SOX9 shRNA silencing AAV

Name 
AAV-h-SOX9-shRNA
Cat No 
shAAV-224033
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SOX9.

shAAV-224033
AAV-h-SOX9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SOX9 (SRY-box 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMD1; CMPD1; SRA1; SRXX2; SRXY10
Description (Vector)
SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Gene ID
6662
Gene Name (Vector)
SRY-box 9
Gene Symbol
SOX9
HGNC ID
HGNC:11204
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_000346
RefSeq Synonyms
NM_000346, BC056420, BC007951,
Species
human
UniGene ID
Hs.647409

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.