human SORCS3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SORCS3.
shAAV-223996
AAV-h-SORCS3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SORCS3 (sortilin related VPS10 domain containing receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SORCS
Description (Vector)
SORCS3 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.
Gene ID
22986
Gene Name (Vector)
sortilin related VPS10 domain containing receptor 3
Gene Symbol
SORCS3
HGNC ID
HGNC:16699
ORF Size (aa)
3669
ORF Size (bp)
3669 bp
RefSeq ID
NM_014978
RefSeq Synonyms
NM_014978, BC117417,
Species
human
UniGene ID
Hs.671950
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.