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human SOAT1 shRNA silencing AAV

Name 
AAV-h-SOAT1-shRNA
Cat No 
shAAV-223967
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SOAT1.

shAAV-223967
AAV-h-SOAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SOAT1 (sterol O-acyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACACT; ACAT; ACAT-1; ACAT1; SOAT; STAT
Description (Vector)
SOAT1 belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
Gene ID
6646
Gene Name (Vector)
sterol O-acyltransferase 1
Gene Symbol
SOAT1
HGNC ID
HGNC:11177
ORF Size (aa)
1653
ORF Size (bp)
1653 bp
RefSeq ID
NM_003101
RefSeq Synonyms
NM_003101, NM_001252512, NM_001252511, BC028940,
Species
human
UniGene ID
Hs.496383

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.