human SNRPC shRNA silencing AAV

Name
AAV-h-SNRPC-shRNA

Cat No
shAAV-223880

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SNRPC.

shAAV-223880

AAV-h-SNRPC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNRPC (small nuclear ribonucleoprotein polypeptide C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

U1C; Yhc1

Description (Vector)

SNRPC encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.

Gene ID

6631

Gene Name (Vector)

small nuclear ribonucleoprotein polypeptide C

Gene Symbol

SNRPC

HGNC ID

HGNC:11157

ORF Size (aa)

480

RefSeq ID

NM_003093

RefSeq Synonyms

NM_003093, BC121083, BC121082,

Species

human

UniGene ID

Hs.1063

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.