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human SNRNP35 shRNA silencing AAV

Name 
AAV-h-SNRNP35-shRNA
Cat No 
shAAV-223866
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SNRNP35.

shAAV-223866
AAV-h-SNRNP35-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNRNP35 (small nuclear ribonucleoprotein U11/U12 subunit 35). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HM-1; U1SNRNPBP
Description (Vector)
SNRNP35 is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Gene ID
11066
Gene Name (Vector)
small nuclear ribonucleoprotein U11/U12 subunit 35
Gene Symbol
SNRNP35
HGNC ID
HGNC:30852
ORF Size (aa)
741
RefSeq ID
NM_022717
RefSeq Synonyms
NM_180699, NM_022717, BC111955, BC093671, BC054034, BC047678, BC009622,
Species
human
UniGene ID
Hs.632738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.