human SMCR8 shRNA silencing AAV

Name 
AAV-h-SMCR8-shRNA
Cat No 
shAAV-223745
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SMCR8.

shAAV-223745
AAV-h-SMCR8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMCR8 (Smith-Magenis syndrome chromosome region, candidate 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
guanine nucleotide exchange protein SMCR8; smith-Magenis syndrome chromosomal region candidate gene 8 protein
Description (eCommerce)
Smith-Magenis syndrome chromosomal region candidate gene 8 (SMCR8) has been found to be expressed in all tissues tested [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEV9].
Gene ID
140775
Gene Name (eCommerce)
Smith-Magenis syndrome chromosome region, candidate 8
Gene Name (Vector)
Smith-Magenis syndrome chromosome region, candidate 8
Gene Symbol
SMCR8
HGNC ID
HGNC:17921
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2814
ORF Size (bp)
2814 bp
Protein Name (eCommerce)
Smith-Magenis syndrome chromosomal region candidate gene 8 protein
RefSeq ID
NM_144775
RefSeq Synonyms
NM_144775, BC142680,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Smith-Magenis syndrome chromosomal region candidate gene 8 (SMCR8) has been found to be expressed in all tissues tested [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEV9].
UniGene ID
Hs.707728
UniProt ID (eCommerce)
Q8TEV9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.