human SLK shRNA silencing AAV

Name
AAV-h-SLK-shRNA

Cat No
shAAV-223670

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SLK.

shAAV-223670

AAV-h-SLK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLK (STE20 like kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bA16H23.1; CTCL tumor antigen se20-9; hSLK; Long Ste20-like Kinase; LOSK; se20-9; serine/threonine-protein kinase 2; SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase; SNF1 sucrose nonfermenting like kinase; STE20-like kinase; STE20-like serine/threonine-protein kinase; STE20-related kinase; Ste20-related serine/threonine kinase; STE20-related serine/threonine-protein kinase; STK2

Description (eCommerce)

Ste20-like kinase (SLK) plays a role in cytoskeletal organization during cell spreading and can induce actin stress fiber disassembly. SLK is a serine/threonine kinase that is thought to be regulated by casein kinase 2 (CK2) and is also involved in apoptosis.

Gene ID

9748

Gene Name (eCommerce)

STE20 like kinase

Gene Name (Vector)

STE20 like kinase

Gene Symbol

SLK

HGNC ID

HGNC:11088

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3615

ORF Size (bp)

3615 bp

Protein Name (eCommerce)

STE20-like serine/threonine-protein kinase

RefSeq ID

NM_014720

RefSeq Synonyms

NM_014720, NM_001304743, BC111565,

Research Areas

Apoptosis,Cell Cycle,DNA Damage/Repair,Kinase/Phosphatase,Meiosis

Research Areas (Faceted)

cell_biology,cell_cycle,developmental_biology,genetics,signal_transduction,transcription_translation

Species

human

Target Sentence

Ste20-like kinase (SLK) plays a role in cytoskeletal organization during cell spreading and can induce actin stress fiber disassembly. SLK is a serine/threonine kinase that is thought to be regulated by casein kinase 2 (CK2) and is also involved in apoptosis.

UniGene ID

Hs.591922

UniProt ID (eCommerce)

Q9H2G2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.