human SLC9A3R2 shRNA silencing AAV

Name
AAV-h-SLC9A3R2-shRNA

Cat No
shAAV-223618

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC9A3R2.

shAAV-223618

AAV-h-SLC9A3R2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC9A3R2 (SLC9A3 regulator 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1

Description (Vector)

SLC9A3R2 encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

9351

Gene Name (Vector)

SLC9A3 regulator 2

Gene Symbol

SLC9A3R2

HGNC ID

HGNC:11076

ORF Size (aa)

1014

RefSeq ID

NM_004785

RefSeq Synonyms

NM_004785, NM_001252076, NM_001252075, NM_001252073, NM_001130012, BC106001, BC014513,

Species

human

UniGene ID

Hs.440896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.