human SLC8A3 shRNA silencing AAV

Name
AAV-h-SLC8A3-shRNA

Cat No
shAAV-223609

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC8A3.

shAAV-223609

AAV-h-SLC8A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC8A3 (solute carrier family 8 member A3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NCX3

Description (Vector)

SLC8A3 encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

Gene ID

6547

Gene Name (Vector)

solute carrier family 8 member A3

Gene Symbol

SLC8A3

HGNC ID

HGNC:11070

ORF Size (aa)

2784

ORF Size (bp)

2784 bp

RefSeq ID

NM_033262

RefSeq Synonyms

NM_183002, NM_182936, NM_182932, NM_058240, NM_033262, NM_001130417, BC160014,

Species

human

UniGene ID

Hs.337696

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.