human SLC6A3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLC6A3.
shAAV-223569
AAV-h-SLC6A3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLC6A3 (solute carrier family 6 member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DAT; DAT1; PKDYS
Description (Vector)
SLC6A3 encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
Gene ID
6531
Gene Name (Vector)
solute carrier family 6 member 3
Gene Symbol
SLC6A3
HGNC ID
HGNC:11049
ORF Size (aa)
1863
ORF Size (bp)
1863 bp
RefSeq ID
NM_001044
RefSeq Synonyms
NM_001044, BC133003, BC132977,
Species
human
UniGene ID
Hs.406
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.