human SLC4A11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLC4A11.
shAAV-223512
AAV-h-SLC4A11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLC4A11 (solute carrier family 4 member 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BTR1; CDPD1; CHED; CHED2; dJ794I6.2; NABC1
Description (Vector)
SLC4A11 encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.
Gene ID
83959
Gene Name (Vector)
solute carrier family 4 member 11
Gene Symbol
SLC4A11
HGNC ID
HGNC:16438
ORF Size (aa)
2676
ORF Size (bp)
2676 bp
RefSeq ID
NM_032034
RefSeq Synonyms
NM_032034, NM_001174090, NM_001174089, BC110540,
Species
human
UniGene ID
Hs.105607
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.