human SLC39A8 shRNA silencing AAV

Name
AAV-h-SLC39A8-shRNA

Cat No
shAAV-223467

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SLC39A8.

shAAV-223467

AAV-h-SLC39A8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC39A8 (solute carrier family 39 member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8

Description (Vector)

SLC39A8 encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene ID

64116

Gene Name (Vector)

solute carrier family 39 member 8

Gene Symbol

SLC39A8

HGNC ID

HGNC:20862

ORF Size (aa)

1383

ORF Size (bp)

1383 bp

RefSeq ID

NM_022154

RefSeq Synonyms

NM_022154, NM_001135148, NM_001135147, NM_001135146, BC012125,

Species

human

UniGene ID

Hs.288034

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.