human SLC29A3 shRNA silencing AAV

Name
AAV-h-SLC29A3-shRNA

Cat No
shAAV-223330

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SLC29A3.

shAAV-223330

AAV-h-SLC29A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC29A3 (solute carrier family 29 member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ENT3; HCLAP; HJCD; PHID

Description (Vector)

SLC29A3 encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.

Gene ID

55315

Gene Name (Vector)

solute carrier family 29 member 3

Gene Symbol

SLC29A3

HGNC ID

HGNC:23096

ORF Size (aa)

1428

ORF Size (bp)

1428 bp

RefSeq ID

NM_018344

RefSeq Synonyms

NM_018344, NM_001174098, BC120997, BC120996,

Species

human

UniGene ID

Hs.438419

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.