human SLC25A13 shRNA silencing AAV

Cat. No: shAAV-223223

Availability: 6-8 weeks

Name: AAV-h-SLC25A13-shRNA

This is an AAV expressing shRNA for silencing of Human SLC25A13.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC25A13
Gene Name: solute carrier family 25 member 13
Gene ID: 10165
Gene Synonyms: ARALAR2; CITRIN; CTLN2
ORF Size: 2028 bp
RefSeq#: NM_014251
Gene Description: SLC25A13 is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.489190
HGNC ID: HGNC:10983