human SLC18A2 shRNA silencing AAV

Name
AAV-h-SLC18A2-shRNA

Cat No
shAAV-223157

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC18A2.

shAAV-223157

AAV-h-SLC18A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC18A2 (solute carrier family 18 member A2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SVAT; SVMT; VAT2; VMAT2

Description (Vector)

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 (PubMed 7905859)). See also SLC18A1 (MIM 193002).(supplied by OMIM, Jan 2011)

Gene ID

6571

Gene Name (Vector)

solute carrier family 18 member A2

Gene Symbol

SLC18A2

HGNC ID

HGNC:10935

ORF Size (aa)

1545

ORF Size (bp)

1545 bp

RefSeq ID

NM_003054

RefSeq Synonyms

NM_003054, BC108928, BC108927,

Species

human

UniGene ID

Hs.654476

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.