human SIX1 shRNA silencing AAV

Name 
AAV-h-SIX1-shRNA
Cat No 
shAAV-223031
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SIX1.

shAAV-223031
AAV-h-SIX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SIX1 (SIX homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BOS3; DFNA23; TIP39
Description (Vector)
SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
Gene ID
6495
Gene Name (Vector)
SIX homeobox 1
Gene Symbol
SIX1
HGNC ID
HGNC:10887
ORF Size (aa)
855
RefSeq ID
NM_005982
RefSeq Synonyms
NM_005982, BC008874,
Species
human
UniGene ID
Hs.716658

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.