human SIVA1 shRNA silencing AAV

Name
AAV-h-SIVA1-shRNA

Cat No
shAAV-223030

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SIVA1.

shAAV-223030

AAV-h-SIVA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SIVA1 (SIVA1 apoptosis inducing factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD27BP; SIVA; Siva-1; Siva-2

Description (Vector)

SIVA1 encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.

Gene ID

10572

Gene Name (Vector)

SIVA1 apoptosis inducing factor

Gene Symbol

SIVA1

HGNC ID

HGNC:17712

ORF Size (aa)

333

RefSeq ID

NM_006427

RefSeq Synonyms

NM_021709, NM_006427, BC034562,

Species

human

UniGene ID

Hs.112058

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.