human SIM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SIM2.
shAAV-223005
AAV-h-SIM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SIM2 (single-minded family bHLH transcription factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe15; HMC13F06; HMC29C01; SIM
Description (Vector)
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on the mapping position, its potential function as transcriptional repressor and similarity to Drosophila sim, it is proposed that SIM2 may contribute to some specific Down syndrome phenotypes
Gene ID
6493
Gene Name (Vector)
single-minded family bHLH transcription factor 2
Gene Symbol
SIM2
HGNC ID
HGNC:10883
ORF Size (aa)
1713
ORF Size (bp)
1713 bp
RefSeq ID
NM_005069
RefSeq Synonyms
NM_009586, NM_005069, BC110444,
Species
human
UniGene ID
Hs.146186
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.