human SIAE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SIAE.
shAAV-222978
AAV-h-SIAE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SIAE (sialic acid acetylesterase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIS6; CSE-C; CSEC; LSE; YSG2
Description (Vector)
SIAE encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.
Gene ID
54414
Gene Name (Vector)
sialic acid acetylesterase
Gene Symbol
SIAE
HGNC ID
HGNC:18187
ORF Size (aa)
1572
ORF Size (bp)
1572 bp
RefSeq ID
NM_170601
RefSeq Synonyms
NM_170601, NM_001199922, BC068450, BC040966,
Species
human
UniGene ID
Hs.10056
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.