human SHQ1 shRNA silencing AAV

Name
AAV-h-SHQ1-shRNA

Cat No
shAAV-222962

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SHQ1.

shAAV-222962

AAV-h-SHQ1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GRIM-1; Shq1p

Description (Vector)

SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase (see MIM 602322) (Grozdanov et al., 2009 (PubMed 19383767)).(supplied by OMIM, Dec 2010)

Gene ID

55164

Gene Name (Vector)

SHQ1, H/ACA ribonucleoprotein assembly factor

Gene Symbol

SHQ1

HGNC ID

HGNC:25543

ORF Size (aa)

1734

ORF Size (bp)

1734 bp

RefSeq ID

NM_018130

RefSeq Synonyms

NM_018130, BC047879, BC039830, BC032671, BC025270, BC017274, BC017204,

Species

human

UniGene ID

Hs.606584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.