human SH3TC2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SH3TC2.
shAAV-222919
AAV-h-SH3TC2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SH3TC2 (SH3 domain and tetratricopeptide repeats 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT4C; MNMN
Description (Vector)
SH3TC2 encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons.
Gene ID
79628
Gene Name (Vector)
SH3 domain and tetratricopeptide repeats 2
Gene Symbol
SH3TC2
HGNC ID
HGNC:29427
ORF Size (aa)
3846
ORF Size (bp)
3846 bp
RefSeq ID
NM_024577
RefSeq Synonyms
NM_024577, BC114486, BC113879,
Species
human
UniGene ID
Hs.483784
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.