human SH3RF1 shRNA silencing AAV

Name 
AAV-h-SH3RF1-shRNA
Cat No 
shAAV-222914
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SH3RF1.

shAAV-222914
AAV-h-SH3RF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SH3RF1 (SH3 domain containing ring finger 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
POSH; RNF142; SH3MD2
Description (Vector)
SH3RF1 encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
Gene ID
57630
Gene Name (Vector)
SH3 domain containing ring finger 1
Gene Symbol
SH3RF1
HGNC ID
HGNC:17650
ORF Size (aa)
3171
ORF Size (bp)
3171 bp
RefSeq ID
NM_020870
RefSeq Synonyms
NM_020870, BC053671,
Species
human
UniGene ID
Hs.301804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.