human SGSM3 shRNA silencing AAV

Name 
AAV-h-SGSM3-shRNA
Cat No 
shAAV-222871
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SGSM3.

shAAV-222871
AAV-h-SGSM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SGSM3 (small G protein signaling modulator 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIP85; MAP; merlin binding protein; merlin-associated protein; RABGAP5; RabGAP-5; rabGAPLP; rab-GTPase-activating protein-like protein; RUN and SH3 containing 3; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; RUSC3; RUTBC3; small G protein signaling modulator 3; small G protein signaling modulator 3 protein
Description (eCommerce)
Small G protein signaling modulator 3 (SGSM3) may play a cooperative role in NF2-mediated growth suppression of cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96HU1].
Gene ID
27352
Gene Name (eCommerce)
small G protein signaling modulator 3
Gene Name (Vector)
small G protein signaling modulator 3
Gene Symbol
SGSM3
HGNC ID
HGNC:25228
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2250
ORF Size (bp)
2250 bp
Protein Name (eCommerce)
Small G protein signaling modulator 3
RefSeq ID
NM_015705
RefSeq Synonyms
NM_015705, NM_001301849, BC008078,
Research Areas
Cell Cycle
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Small G protein signaling modulator 3 (SGSM3) may play a cooperative role in NF2-mediated growth suppression of cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96HU1].
UniGene ID
Hs.474914
UniProt ID (eCommerce)
Q96HU1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.