human SGPP2 shRNA silencing AAV

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

SGPP2

Gene Name

sphingosine-1-phosphate phosphatase 2

Gene ID

130367

Gene Synonyms

SPP2; SPPase2

ORF Size

1200 bp

RefSeq#

NM_152386

Gene Description

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P (Ogawa et al., 2003 (PubMed 12411432)).(supplied by OMIM, Jun 2009)

UniGene ID

Hs.591604

HGNC ID

HGNC:19953