human SGEF shRNA silencing AAV

Name 
AAV-h-SGEF-shRNA
Cat No 
shAAV-222848
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ARHGEF26.

shAAV-222848
AAV-h-SGEF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARHGEF26 (Rho guanine nucleotide exchange factor 26). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CSGEF; HMFN1864; SGEF
Description (Vector)
ARHGEF26 encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
26084
Gene Name (Vector)
Rho guanine nucleotide exchange factor 26
Gene Symbol
ARHGEF26
ORF Size (aa)
2616
ORF Size (bp)
2616 bp
RefSeq ID
NM_015595
RefSeq Synonyms
NM_015595, NM_001251963, NM_001251962, BC078655, BC016628,
Species
human
UniGene ID
Hs.240845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.