human SF1 shRNA silencing AAV

Name
AAV-h-SF1-shRNA

Cat No
shAAV-222754

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SF1.

shAAV-222754

AAV-h-SF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SF1 (splicing factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BBP; D11S636; mammalian branch point-binding protein; MBBP; splicing factor 1; transcription factor ZFM1; ZCCHC25; ZFM1; zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162

Description (eCommerce)

Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor. SF1 specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly [taken from NCBI Entrez Gene (Gene ID: 7536)].

Description (Vector)

SF1 encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants.

Gene ID

7536

Gene Name (eCommerce)

splicing factor 1

Gene Name (Vector)

splicing factor 1

Gene Symbol

SF1

HGNC ID

HGNC:12950

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2022

ORF Size (bp)

2022 bp

Protein Name (eCommerce)

Splicing factor 1

RefSeq ID

NM_004630

RefSeq Synonyms

NM_201998, NM_201997, NM_201995, NM_004630, NM_001346410, NM_001346409, NM_001346364, NM_001346363, NM_001178031, NM_001178030, BC038446, BC020217, BC008724, BC008080,

Research Areas

Cell Cycle,Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,transcription_translation,cell_biology

Species

human

Target Sentence

UniGene ID

Hs.502829

UniProt ID (eCommerce)

Q15637

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.