human SERPINF2 shRNA silencing AAV

Name
AAV-h-SERPINF2-shRNA

Cat No
shAAV-222709

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SERPINF2.

shAAV-222709

AAV-h-SERPINF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SERPINF2 (serpin family F member 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A2AP; AAP; ALPHA-2-PI; API; PLI

Description (Vector)

SERPINF2 encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

5345

Gene Name (Vector)

serpin family F member 2

Gene Symbol

SERPINF2

HGNC ID

HGNC:9075

ORF Size (aa)

1476

ORF Size (bp)

1476 bp

RefSeq ID

NM_000934

RefSeq Synonyms

NM_001165921, NM_001165920, NM_000934, BC031592,

Species

human

UniGene ID

Hs.159509

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.