human SEPT6 shRNA silencing AAV

Name
AAV-h-SEPT6-shRNA

Cat No
shAAV-222610

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SEPT6.

shAAV-222610

AAV-h-SEPT6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEPT6 (septin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SEP2; SEPT2

Description (Vector)

6-Sep is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. 6-Sep encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Gene ID

23157

Gene Name (Vector)

septin 6

Gene Symbol

6-Sep

HGNC ID

HGNC:15848

ORF Size (aa)

1305

ORF Size (bp)

1305 bp

RefSeq ID

NM_015129

RefSeq Synonyms

NM_145802, NM_145800, NM_145799, NM_015129, BC069231, BC036240, BC011922, BC009291,

Species

human

UniGene ID

Hs.496666

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.