human SENP5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SENP5.
shAAV-222576
AAV-h-SENP5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SENP5 (SUMO1/sentrin specific peptidase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 (PubMed 16738315)).(supplied by OMIM, Jun 2009)
Gene ID
205564
Gene Name (Vector)
SUMO1/sentrin specific peptidase 5
Gene Symbol
SENP5
HGNC ID
HGNC:28407
ORF Size (aa)
2268
ORF Size (bp)
2268 bp
RefSeq ID
NM_152699
RefSeq Synonyms
NM_152699, NM_001308045, BC030705,
Species
human
UniGene ID
Hs.240770
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.