human SELL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SELL.
shAAV-222516
AAV-h-SELL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SELL (selectin L). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1
Description (Vector)
SELL encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
Gene ID
6402
Gene Name (Vector)
selectin L
Gene Symbol
SELL
HGNC ID
HGNC:10720
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_000655
RefSeq Synonyms
NM_000655, BC020758,
Species
human
UniGene ID
Hs.82848
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.