human SEC61A2 shRNA silencing AAV

Name
AAV-h-SEC61A2-shRNA

Cat No
shAAV-222503

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SEC61A2.

shAAV-222503

AAV-h-SEC61A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEC61A2 (Sec61 translocon alpha 2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

SEC61A2 has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants.

Gene ID

55176

Gene Name (Vector)

Sec61 translocon alpha 2 subunit

Gene Symbol

SEC61A2

HGNC ID

HGNC:17702

ORF Size (aa)

1257

ORF Size (bp)

1257 bp

RefSeq ID

NM_018144

RefSeq Synonyms

NM_018144, NM_001142628, NM_001142627, BC026179,

Species

human

UniGene ID

Hs.112955

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.