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human SCO2 shRNA silencing AAV

Name 
AAV-h-SCO2-shRNA
Cat No 
shAAV-222384
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCO2.

shAAV-222384
AAV-h-SCO2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCO2 (SCO2, cytochrome c oxidase assembly protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CEMCOX1; MYP6; SCO1L
Description (Vector)
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.
Gene ID
9997
Gene Name (Vector)
SCO2, cytochrome c oxidase assembly protein
Gene Symbol
SCO2
HGNC ID
HGNC:10604
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_005138
RefSeq Synonyms
NM_005138, NM_001169111, NM_001169110, NM_001169109, BC102025, BC102024,
Species
human
UniGene ID
Hs.718545

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.