human SCNN1G shRNA silencing AAV

Name 
AAV-h-SCNN1G-shRNA
Cat No 
shAAV-222381
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCNN1G.

shAAV-222381
AAV-h-SCNN1G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCNN1G (sodium channel epithelial 1 gamma subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BESC3; ENaCg; ENaCgamma; PHA1; SCNEG
Description (Vector)
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
Gene ID
6340
Gene Name (Vector)
sodium channel epithelial 1 gamma subunit
Gene Symbol
SCNN1G
HGNC ID
HGNC:10602
ORF Size (aa)
1950
ORF Size (bp)
1950 bp
RefSeq ID
NM_001039
RefSeq Synonyms
NM_001039, BC069652, BC059391,
Species
human
UniGene ID
Hs.371727

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.