human SCLY shRNA silencing AAV

Name 
AAV-h-SCLY-shRNA
Cat No 
shAAV-222358
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCLY.

shAAV-222358
AAV-h-SCLY-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCLY (selenocysteine lyase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hSCL; SCL; selenocysteine lyase
Description (eCommerce)
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008] [taken from NCBI Entrez Gene (Gene ID: 51540)].
Description (Vector)
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 (PubMed 10692412)).(supplied by OMIM, Mar 2008)
Gene ID
51540
Gene Name (eCommerce)
selenocysteine lyase
Gene Name (Vector)
selenocysteine lyase
Gene Symbol
SCLY
HGNC ID
HGNC:18161
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
Protein Name (eCommerce)
Selenocysteine lyase
RefSeq ID
NM_016510
RefSeq Synonyms
NM_016510, BC007891,
Research Areas
Cell Biology,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008] [taken from NCBI Entrez Gene (Gene ID: 51540)].
UniGene ID
Hs.709612
UniProt ID (eCommerce)
Q96I15

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.