human SCG2 shRNA silencing AAV

Name
AAV-h-SCG2-shRNA

Cat No
shAAV-222328

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SCG2.

shAAV-222328

AAV-h-SCG2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCG2 (secretogranin II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CHGC; EM66; SgII; SN

Description (Vector)

SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

Gene ID

7857

Gene Name (Vector)

secretogranin II

Gene Symbol

SCG2

HGNC ID

HGNC:10575

ORF Size (aa)

1854

ORF Size (bp)

1854 bp

RefSeq ID

NM_003469

RefSeq Synonyms

NM_003469, BC022509,

Species

human

UniGene ID

Hs.516726

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.