human SC5DL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SC5D.
shAAV-222287
AAV-h-SC5DL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SC5D (sterol-C5-desaturase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ERG3; S5DES; SC5DL
Description (Vector)
SC5DL encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.
Gene ID
6309
Gene Name (Vector)
sterol-C5-desaturase
Gene Symbol
SC5D
HGNC ID
HGNC:10547
ORF Size (aa)
900
RefSeq ID
NM_006918
RefSeq Synonyms
NM_006918, NM_001024956, BC050427, BC012333,
Species
human
UniGene ID
Hs.287749
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.