human SAR1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SAR1B.
shAAV-222250
AAV-h-SAR1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SAR1B (secretion associated Ras related GTPase 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ANDD; CMRD; GTBPB; SARA2
Description (Vector)
SAR1B is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
Gene ID
51128
Gene Name (Vector)
secretion associated Ras related GTPase 1B
Gene Symbol
SAR1B
HGNC ID
HGNC:10535
ORF Size (aa)
597
RefSeq ID
NM_016103
RefSeq Synonyms
NM_016103, NM_001033503, BC093034, BC002847,
Species
human
UniGene ID
Hs.432984
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.