human S100A6 shRNA silencing AAV

Name
AAV-h-S100A6-shRNA

Cat No
shAAV-222173

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human S100A6.

shAAV-222173

AAV-h-S100A6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human S100A6 (S100 calcium binding protein A6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2A9; 5B10; CABP; CACY; PRA

Description (Vector)

S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Gene ID

6277

Gene Name (Vector)

S100 calcium binding protein A6

Gene Symbol

S100A6

HGNC ID

HGNC:10496

ORF Size (aa)

273

RefSeq ID

NM_014624

RefSeq Synonyms

NM_014624, BC009017, BC001431,

Species

human

UniGene ID

Hs.275243

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.