human S100A4 shRNA silencing AAV

Name
AAV-h-S100A4-shRNA

Cat No
shAAV-222169

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human S100A4.

shAAV-222169

AAV-h-S100A4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human S100A4 (S100 calcium binding protein A4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98

Description (Vector)

S100A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

6275

Gene Name (Vector)

S100 calcium binding protein A4

Gene Symbol

S100A4

HGNC ID

HGNC:10494

ORF Size (aa)

306

RefSeq ID

NM_002961

RefSeq Synonyms

NM_019554, NM_002961, BC016300, BC000838,

Species

human

UniGene ID

Hs.654444

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.