human RTN4R shRNA silencing AAV

Name 
AAV-h-RTN4R-shRNA
Cat No 
shAAV-222095
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RTN4R.

shAAV-222095
AAV-h-RTN4R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RTN4R (reticulon 4 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NGR; NOGOR
Description (Vector)
RTN4R encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Gene ID
65078
Gene Name (Vector)
reticulon 4 receptor
Gene Symbol
RTN4R
HGNC ID
HGNC:18601
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_023004
RefSeq Synonyms
NM_023004, BC011787,
Species
human
UniGene ID
Hs.30868

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.