human RRAGD shRNA silencing AAV

Name 
AAV-h-RRAGD-shRNA
Cat No 
shAAV-221992
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RRAGD.

shAAV-221992
AAV-h-RRAGD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RRAGD (Ras related GTP binding D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA11D8.2.1; Rag D; Rag D protein; RAGD; ras-related GTP-binding protein D
Description (eCommerce)
Ras-related GTP-binding protein D (RRAGD) is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways [taken from NCBI Entrez Gene (Gene ID: 58528)].
Description (Vector)
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.(supplied by OMIM, Apr 2004)
Gene ID
58528
Gene Name (eCommerce)
Ras related GTP binding D
Gene Name (Vector)
Ras related GTP binding D
Gene Symbol
RRAGD
HGNC ID
HGNC:19903
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
750
Protein Name (eCommerce)
Ras-related GTP-binding protein D
RefSeq ID
NM_021244
RefSeq Synonyms
NM_021244, BC003088,
Research Areas
Lysosome,mTOR Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Ras-related GTP-binding protein D (RRAGD) is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways [taken from NCBI Entrez Gene (Gene ID: 58528)].
UniGene ID
Hs.31712
UniProt ID (eCommerce)
Q9NQL2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.