human RRAGB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RRAGB.
shAAV-221990
AAV-h-RRAGB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RRAGB (Ras related GTP binding B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bA465E19.1; RAGB
Description (Vector)
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
Gene ID
10325
Gene Name (Vector)
Ras related GTP binding B
Gene Symbol
RRAGB
HGNC ID
HGNC:19901
ORF Size (aa)
1041
ORF Size (bp)
1041 bp
RefSeq ID
NM_006064
RefSeq Synonyms
NM_016656, NM_006064, BC034726,
Species
human
UniGene ID
Hs.50282
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.