human RPRD1B shRNA silencing AAV

Name 
AAV-h-RPRD1B-shRNA
Cat No 
shAAV-221801
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPRD1B.

shAAV-221801
AAV-h-RPRD1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPRD1B (regulation of nuclear pre-mRNA domain containing 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C20orf77; Cell cycle-related and expression-elevated protein in tumor; cell-cycle related and expression-elevated protein in tumor; CREPT; dJ1057B20.2; K-H; Ku70-binding protein 5-Hera; Kub5-Hera; NET60; regulation of nuclear pre-mRNA domain-containing protein 1B
Description (eCommerce)
RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. RPRD1B is a transcriptional regulator that promotes cell proliferation and enhances the transcription of a number of cell cycle-related genes including CCND1, CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQG5].
Gene ID
58490
Gene Name (eCommerce)
regulation of nuclear pre-mRNA domain containing 1B
Gene Name (Vector)
regulation of nuclear pre-mRNA domain containing 1B
Gene Symbol
RPRD1B
HGNC ID
HGNC:16209
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
981
ORF Size (bp)
981 bp
Protein Name (eCommerce)
Regulation of nuclear pre-mRNA domain-containing protein 1B
RefSeq ID
NM_021215
RefSeq Synonyms
NM_021215, BC033629,
Research Areas
Cell Cycle,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. RPRD1B is a transcriptional regulator that promotes cell proliferation and enhances the transcription of a number of cell cycle-related genes including CCND1, CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQG5].
UniGene ID
Hs.278839
UniProt ID (eCommerce)
Q9NQG5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.