human RPL23 shRNA silencing AAV

Name 
AAV-h-RPL23-shRNA
Cat No 
shAAV-221634
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPL23.

shAAV-221634
AAV-h-RPL23-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPL23 (ribosomal protein L23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
60S ribosomal protein L17; 60S ribosomal protein L23; L23; large ribosomal subunit protein uL14; ribosomal protein L17; rpL17
Description (eCommerce)
Ribosomal Protein L23/RPL23 belongs to the ribosomal protein L14P family [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P62829].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
9349
Gene Name (eCommerce)
ribosomal protein L23
Gene Name (Vector)
ribosomal protein L23
Gene Symbol
RPL23
HGNC ID
HGNC:10316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
423
Protein Name (eCommerce)
60S ribosomal protein L23
RefSeq ID
NM_000978
RefSeq Synonyms
NM_000978, BC106061, BC104651, BC062716, BC010114,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,p53 Signaling,RNA Processing,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Ribosomal Protein L23/RPL23 belongs to the ribosomal protein L14P family [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P62829].
UniGene ID
Hs.406300
UniProt ID (eCommerce)
P62829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.