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human RPL18 shRNA silencing AAV

Name 
AAV-h-RPL18-shRNA
Cat No 
shAAV-221611
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPL18.

shAAV-221611
AAV-h-RPL18-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPL18 (ribosomal protein L18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
60S ribosomal protein L18; L18; large ribosomal subunit protein eL18
Description (eCommerce)
60S ribosomal protein L18 (RPL18) is a member of the L18E family of ribosomal proteins and a component of the 60S subunit [taken from NCBI Entrez Gene (Gene ID: 6141)].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
6141
Gene Name (eCommerce)
ribosomal protein L18
Gene Name (Vector)
ribosomal protein L18
Gene Symbol
RPL18
HGNC ID
HGNC:10310
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
567
Protein Name (eCommerce)
60S ribosomal protein L18
RefSeq ID
NM_000979
RefSeq Synonyms
NM_001270490, NM_000979, BC021743, BC009708, BC000374,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
60S ribosomal protein L18 (RPL18) is a member of the L18E family of ribosomal proteins and a component of the 60S subunit [taken from NCBI Entrez Gene (Gene ID: 6141)].
UniGene ID
Hs.515517
UniProt ID (eCommerce)
Q07020

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.